Adenosine-induced atrial fibrillation during fractional flow reserve measurement

Adenosine-induced atrial fibrillation during fractional flow reserve measurement.

We present the case of a 44 year-old man referred for coronary angiography with a history of coronary artery disease. Following administration of intra-coronary adenosine for fractional flow reserve (FFR) assessment, the patient developed atrial fibrillation (AF). While well described during non-invasive stress testing, this is the first description in the literature of AF following adenosi...

Adenosine-Induced Atrial Fibrillation

Coronary pressure measurement and fractional flow reserve.

The shortcomings of coronary arteriography to assess the physiological significance of coronary stenoses have been recognised for decades ; therefore, the importance of additional physiological techniques is beyond doubt. One of the currently available physiological techniques is coronary pressure measurement, which has emerged over the past few years as a major step forward in the invasive ass...

Adenosine-induced atrial fibrillation: insights into mechanism.

A trial fibrillation (AF) is a potential adverse effect of intravenous administration of adenosine. Although the mechanism is not known, this phenomenon is thought to be mediated by adenosine's effects on shortening atrial action potential duration and refractoriness. Because ade-nosine has little effect on atrial conduction velocity, the net effect of adenosine, therefore, is to shorten the wa...

Assessment of increasing intravenous adenosine dose in fractional flow reserve

BACKGROUND Effects of increased adenosine dose in the assessment of fractional flow reserve (FFR) were studied in relation to FFR results, hemodynamic effects and patient discomfort. FFR require maximal hyperemia mediated by adenosine. Standard dose is 140 μg/kg/min administrated intravenously. Higher doses are commonly used in clinical practice, but an extensive comparison between standard int...